Base de dados : HANSEN
Pesquisa : INJECOES SUBCUTANEAS [Descritor de assunto]
Referências encontradas : 6 [refinar]
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Id:18825
Autor:Shepard, C. C; Van Landingham, R; Walker, L. L
Título:Effect of levamisole on Mycobacterium leprae in mice
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Fonte:s.l; s.n; may 1977. 4 p. graf.
Descritores:ADMINISTRACAO ORAL
VACINA BCG
INJECOES SUBCUTÂNEAS
HANSENIASE/imunol
LEVAMISOL/admin
LEVAMISOL/farmacol
MYCOBACTERIUM LEPRAE/ef drogas
MYCOBACTERIUM LEPRAE/cresc
Limites:ANIMAL
CAMUNDONGOS
SUPPORT, U.S. GOV'T, P.H.S.
Meio Eletrônico: - .
Localização:BR191.1; 00596/s


  2 / 6 HANSEN  
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Id:18225
Autor:Shepard, Charles C; Walker, Laura L; Van Landingham, Rosalind
Título:Heat stability of Mycobacterium leprae immunogenicity
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Fonte:s.l; s.n; oct. 1978. 7 p. tab, graf.
Resumo:The protection provided to mice by vaccines administered intradermally was measured after footpad challenge with Mycobacterium leprae. The protection offered by M. leprae suspensions was not decreased when the vaccines were killed by 60 degrees C heat or at the higher temperatures tested, which included 215 degrees C (autoclave). Even highly purified suspensions retained their immunogenicity. In contrast, the vaccine protection provided by intradermal M. bovis (strain BCG) was markedly reduced when heated to 60 degrees C. The enlargement of the lymph nodes regional to the intradermal vaccines was measured and found generally to parallel the vaccine protection provided by M. leprae and by BCG.(AU).
Descritores:MYCOBACTERIUM BOVIS
HANSENIASE/imunol
MYCOBACTERIUM LEPRAE/imunol
INJECOES SUBCUTÂNEAS
INJECOES INTRADERMICAS
VACINA BCG
IMUNIDADE CELULAR
VACINAS BACTERIANAS/admin
VACINAS BACTERIANAS/imunol
VACINAS BACTERIANAS/normas
CONGELAMENTO
 CALOR
Limites:ANIMAL
CAMUNDONGOS
SUPPORT, U.S. GOV'T, P.H.S.
Meio Eletrônico: - .
Localização:BR191.1; 00293/s


  3 / 6 HANSEN  
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Id:18179
Autor:Shepard, Charles C; Walker, Laura L; Van Landingham, Rosalind M; Redus, Martha A
Título:Kinetic testing of drugs against Mycobacterium leprae in mice. Activity of cephaloridine, rifampin, streptovaricin, vadrine, and viomycin
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Fonte:s.l; s.n; jul. 1971. 5 p. tab, graf.
Resumo:A series of drugs that had been found active against Mycobacterium leprae in mice by the continous method of drug administration was tested by the kinetic method. Vadrine and vyomivin were found inactive. Cephaloridine, streptovaricin, and rifampin gave bactericidal-type results. In a second experiment, rifampin was found to have distinct bactericidal effect when given for only 2 days. The plasma levels of rifampin that were associated with bactericidal effect in mice were in the range reported for man receiving acceptable dosages of rifampin. Cephaloridine and, especially, rifampin merit further investigation in clinical trials in leprosy patients, either as single drugs or in combination with other active drugs. The combination of rifampin and dapsone (DDS) or acedapsone (DADDS) appear to provide the advantages of tboth drugs.(AU).
Descritores:ANTIMALARICOS/admin
DAPSONA/admin
INJECOES SUBCUTÂNEAS
HANSENIASE/quimioter
MYCOBACTERIUM LEPRAE/ef drogas
MYCOBACTERIUM LEPRAE/cresc
RIFAMPINA/admin
RIFAMPINA/sangue
VIOMICINA/admin
DIETA
 ESTUDOS DE AVALIACAO
 CINETICA
 MALARIA/sangue
 OXIDIAZOIS/admin
 PIRIDINAS/admin
 ACIDOS SALICILICOS/admin
 ESTREPTOVARICINA/admin
Limites:ANIMAL
CAMUNDONGOS
Meio Eletrônico: - .
Localização:BR191.1; 02305/s


  4 / 6 HANSEN  
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Id:17778
Autor:Shepard, C. C; Van Landingham, R; Walker, L. L
Título:Effect of levamisole on Mycobacterium leprae in mice
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Fonte:s.l; s.n; may 1977. 14 p. tab, graf.
Resumo:Levamisole, an antihelminthic drug that is capable of enhancing immune responses in mice and in humans, was tested in experimental Mycobacterium leprae infections in mice by a number of schedules. Intermittent schedules were used, and administration of the drug was started (i) around the time of inoculation with M. leprae, (ii) when the M. leprae population was approaching the plateau level, (iii) after the onset of the plateau phase, or (iv) after BCG vaccination 28 days following the inoculation with M. leprae. No effect of drug could be discerned with any of the schedules.(AU).
Descritores:MYCOBACTERIUM LEPRAE/ef drogas
MYCOBACTERIUM LEPRAE/cresc
LEVAMISOL/admin
LEVAMISOL/farmacol
HANSENIASE/imunol
INJECOES SUBCUTÂNEAS
VACINA BCG
ADMINISTRACAO ORAL
Limites:ANIMAL
CAMUNDONGOS
SUPPORT, U.S. GOV'T, P.H.S.
Meio Eletrônico: - .
Localização:BR191.1; 00596/s


  5 / 6 HANSEN  
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Id:13371
Autor:Kaplan, Gilla; Walsh, Gerald; Guido, Laarni S; Meyn, Peter; Burkhardt, Rochel A; Abalos, Rodolfo M; Barker, Jeanne; Frindt, Paula A; Fajardo, Tranquilino T; Celona, Roland; Cohn, Zanvil A
Título:Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: langerhans cell recruitment, keratinocyte growth, and enhanced wound healing
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Fonte:s.l; s.n; 1992. 12 p. ilus, tab, graf.
Descritores:CÉLULAS CHO
ESCHERICHIA COLI
FATOR ESTIMULADOR DE COLONIAS DE GRANULOCITOS
MACROFAGOS
HAMSTERS
INJEÇOES INTRADÉRMICAS
INJEÇOES SUBCUTANEAS
CERATINOCITOS
CERATINOCITOS
CERATINOCITOS
CÉLULAS DE LANGERHANS
CÉLULAS DE LANGERHANS
CÉLULAS DE LANGERHANS
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
LEUCOCITOS
LEUCOCITOS
MICROSCOPIA ELETRONICA
PROTEINAS RECOMBINANTES
PROTEINAS RECOMBINANTES
PELE
PELE
PELE
PELE
FATORES DE TEMPO
CICATRIZAÇAO DE FERIDAS
MACROFAGOS/AD/GE/*TU
Limites:ESTUDO COMPARATIVO
Localização:BR191.1; 06422/s


  6 / 6 HANSEN  
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Id:9388
Autor:Lara, C. B
Título:The plancha, or infiltration, method of treatin leprosy
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Fonte:s.l; s.n; 1929. 8 p. ilus.
Descritores:HANSENIASE
HANSENIASE
HANSENIASE
CHAULMOOGRA
 CHAULMOOGRA
 CHAULMOOGRA
 CHAULMOOGRA
 INJEÇOES SUBCUTANEAS
 INJEÇOES INTRADÉRMICAS
Localização:BR191.1; 05099/s



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